Margins have been designed keeping in mind the needs of the healthcare sector; most importantly, self-sealing caps were introduced in response to the cap shortage dilemma experienced recently. As the name suggests, these self-sealing tubes ensure that saliva sample collection is both safe and effective, which is essential in many cases. This self-seal also eliminate the risk of sample loss or contamination, thereby maintaining the quality of the sample. Designed for different testing specifications, the tubes marketed are key in ensuring that health care efforts on prevention, diagnosis, treatment and rehabilitation are effective within the entire world health management system.